Exploring the Impact of Anxiety and Depression on Patients with Chronic Diseases: Understanding the Severity and its Implications for Care.
DOI:
https://doi.org/10.58676/sjmas.v3i2.111Keywords:
Integrated care, Quality of life, Anxiety and depression, Mental health, Chronic diseaseAbstract
Background: Chronic diseases such as diabetes, cardiovascular diseases, and cancer significantly impact patients’ quality of life, not only physically but also mentally. Anxiety and depression are prevalent among individuals with chronic illnesses, affecting up to 40% of patients. Psychological distress, loss of independence, financial burden, and social isolation contribute to mental health deterioration, which in turn can exacerbate disease progression and hinder treatment adherence. Understanding the bidirectional relationship between chronic disease and mental health is crucial for developing holistic care strategies.
Methods and Materials: This study employs a literature-based approach, analyzing peer-reviewed research, World Health Organization (WHO) reports, and patient interviews. Data sources include clinical studies on the psychological effects of chronic illness, socioeconomic analyses, and case studies highlighting patient experiences. The study explores the biological mechanisms linking chronic disease and mental health, such as inflammation, neurotransmitter imbalances, and chronic stress.
Results: Findings indicate that chronic illness patients experience heightened levels of anxiety and depression due to physical limitations, social stigma, and financial strain. Conditions such as chronic pain disrupt sleep and cognitive function, further worsening psychological health. Patients frequently report feelings of helplessness, reduced self-esteem, and social withdrawal. Studies show that mental health challenges in chronic disease patients lead to poorer treatment adherence, increased hospitalization rates, and higher healthcare costs.
Conclusion: Addressing the mental health burden of chronic disease requires integrated care models that combine medical treatment with psychological support. Holistic approaches, including cognitive behavioral therapy (CBT), support groups, and mental health screenings, can improve patient outcomes. Policies should focus on reducing stigma, enhancing accessibility to mental health care, and incorporating mental health services into routine chronic disease management. Future research should explore the long-term effectiveness of mental health interventions on chronic disease progression.
References
Apollo Clinic. (n.d.). Living with a chronic disease: Navigating the impact on quality of life. Retrieved from https://www.apolloclinic.com/blog/living-with-a-chronic-disease
LifeSpan CM. (n.d.). How does chronic illness affect life? Retrieved from https://www.lifespancm.com/how-does-chronic-illness-affect-life
The Sun. (n.d.). I'm ashamed of myself after my chronic illness diagnosis. Retrieved from https://www.thesun.co.uk
The Plot Twist. (n.d.). Loss of identity with chronic illness & sharpened self. Retrieved from https://www.theplottwist.com
BMC Primary Care. (2024). Living with a chronic disease: Insights from patients with a low socioeconomic status. BMC Primary Care. Retrieved from https://bmcprimcare.biomedcentral.com/articles/10.1186/s12875-024-02156-3
PubMed Central. (n.d.). The link between depression and physical symptoms. PMC. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC
Fishbain, D. (n.d.). The association of chronic pain and suicide. Google Scholar. Retrieved from https://scholar.google.com
Health Psychology Research. (n.d.). How addressing mental health can improve chronic disease outcomes and cut costs. Retrieved from https://www.healthpsychologyresearch.com
Cleveland Clinic. (n.d.). Chronic illness and mental health: How they are connected. Retrieved from https://my.clevelandclinic.org
On Your Mind Counselling. (n.d.). Chronic illness and mental health: A personal journey. Retrieved from https://www.onyourmindcounselling.com
World Health Organization. (n.d.). Mental health at work. WHO. Retrieved from https://www.who.int
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Theresa Godiya Akwashiki, Dr. Ghassan Salibi, Prof Nikolaos Tzenios

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.