Racial Comparisons Of Postmenopausal Osteoporosis Between African American And Caucasian Women

Abstract

Background: Osteoporosis is a chronic degenerative metabolic disease of the skeletal system characterized by decreased bone mineral density (BMD), leading to fragile bones prone to fractures. Postmenopausal osteoporosis is particularly prevalent due to the decline in estrogen levels, a hormone essential for maintaining bone health. This study aims to compare the incidence and risk factors of postmenopausal osteoporosis between African American and Caucasian women, focusing on differences in BMD, risk factors, and the effectiveness of screening and treatment methods.

Methods and Materials: This research was conducted at the Southeastern Medical Center, Texas, involving 1,000 postmenopausal women aged 60 or older, with equal representation of 500 African American and 500 Caucasian women. Data collection included demographic information, medical history, and BMD measurements using the General Electric LUNAR DPXIQ Model 2288 DEXA device. Statistical analysis was performed using Chi-square and Fisher's assessment tests to evaluate risk factors such as alcohol intake, smoking, medication usage, and comorbidities. BMI and age evaluations were systematized, and the World Health Organization (WHO) guidelines were used to classify osteoporosis and osteopenia.

Results: The study revealed that Caucasian women had higher alcohol intake, family history of fractures, and greater use of vitamins, calcium, and hormonal treatments compared to African American women. Conversely, African American women exhibited higher rates of comorbidities like diabetes mellitus, hyperthyroidism, kidney diseases, and rheumatoid arthritis. Despite starting menopause with higher BMD levels, African American women were less likely to be prescribed medication for low BMD. Screening rates and adherence to recommended treatments also varied significantly between the two groups.

Conclusion: The findings highlight significant racial disparities in the incidence, risk factors, and management of postmenopausal osteoporosis. Increasing awareness about osteoporosis and promoting lifestyle modifications such as diet, exercise, and cessation of smoking and alcohol consumption can help mitigate these disparities. Future research should focus on developing targeted interventions to improve screening and treatment adherence among African American women, addressing the specific challenges they face in managing bone health.