An Observational Study On Cervical Cancer In Sri Lanka And Its Prevention And Management.

Authors

  • Prabhashi Mannapperuma Charisma University, Kursk State Medical University
  • Dr.Ghassan Salibi Charisma University
  • Professor Nikolaos Tzenios Charisma University https://orcid.org/0000-0002-6679-2296

DOI:

https://doi.org/10.58676/sjmas.v2i2.51

Keywords:

On Cervical Cancer In Sri Lanka , On Cervical Cancer

Abstract

Background: Cervical cancer is a major health concern worldwide, with significant prevalence in Sri Lanka. Despite being preventable through early detection and vaccination, the disease continues to cause high morbidity and mortality among Sri Lankan women, primarily due to late diagnosis and inadequate access to treatment and preventive measures.

Methods and Materials: This observational study employs a cross-sectional design to collect data from a representative sample of Sri Lankan women, using structured questionnaires and interviews. The study aims to determine the prevalence of cervical cancer, identify risk factors, assess awareness and preventive practices, and explore challenges in treatment and prevention. Statistical analysis will be performed on the collected data to achieve these objectives.

Results: The study is expected to provide detailed insights into the prevalence and risk factors of cervical cancer in Sri Lanka, along with the current state of awareness and preventive measures among women. It will also highlight the barriers to effective treatment and prevention, guiding future strategies.

Conclusion: The findings of this study will significantly contribute to understanding the impact of cervical cancer in Sri Lanka, offering evidence-based recommendations for healthcare providers, policymakers, and the community to improve cervical cancer prevention and management strategies, with the ultimate goal of reducing the incidence and mortality rates of the disease in the country.

References

GLOBOCAN 2020. Global Cancer Observatory: Cancer Today [Internet]. Lyon, France:

International Agency for Research on Cancer; 2020 [cited 2021 December 17]. Available

from: https://gco.iarc.fr/today.

Global strategy to accelerate the elimination of cervical cancer as a public health problem.

Geneva: World Health Organization; 2020. License: CC BY-NC-SA 3.0 IGO.

Canfell K, Kim J, Brisson M, et al. Mortality impact of achieving WHO cervical cancer

elimination targets: a comparative modeling analysis in 78 low-income and lower-middle-income countries. Lancet 2020;395:591-603.

Brisson M, Kim J, Canfell K, et al. Impact of HPV vaccination and cervical screening on

cervical cancer elimination: a comparative modeling analysis in 78 low-income and lower-middle-income countries. Lancet 2020;395:575-90.

National Cancer Control Programme, Ministry of Health. Prevention and Early Detection of

Common Gynaecological Cancers. Comprehensive Guidelines for Primary Care Physicians

[Internet]. Ministry of Health, Sri Lanka; 2006 [cited 2020 December 7]. Available from:

https://www.nccp.health.gov.lk/storage/post/pdfs/Gynecological_Cancers.pdf.

Ministry of Health, Nutrition & Indigenous Medicine. Guidelines on Introduction of the Human

Papillomavirus (HPV) vccine into the National Immunization Programme [Internet]. Ministry

of Health; 2017 [cited 2020 December 7]. Available from: https://www.epid.gov.lk/web/

images/pdf/Circulars/HPV/guidelines_hpv.pdf

Introducing and scaling up testing for human papillomavirus as part of a comprehensive

programme for preventing and controlling cervical cancer: a Step-by-step guide. Geneva:

World Health Organization, 2020. License: CC BY-NC-SA 3.0 IGO

World Health Organization. (2019) WHO guidelines for the use of thermal ablation for cervical

pre-cancer lesions. https://apps.who.int/iris/handle/10665/329299. License: CC BY-NC-SA

National Cancer Control Programme, Ministry of Health Sri Lanka Cancer Incidence Data 2019, Accessed January 1 2023 at: https://www.nccp.health.gov.lk/storage/post/pdfs/Cancer%20Incidence%20Data%20Book-2019_compressed.pdf

Joseph N, Gunasekera S, Ariyaratne Y, Choudhury A. Clinical oncology in Sri Lanka: embracing the promise of the future. Int J Radiat Oncol Biol Phys. 2019;105(03):466–470. [PubMed] [Google Scholar]

Adikari P S, Pathirathna K, Kumarawansa W, Koggalage P D. Role of MOH as a grassroots public health manager in preparedness and response for COVID-19 pandemic in Sri Lanka. AIMS Public Health. 2020;7(03):606–619. [PMC free article] [PubMed] [Google Scholar]

Gamage G, Rajapaksa L, Abeysinghe M RN, de Silva A.Prevalence of Human Papilloma Virus Infection and the Burden of Cervical Cancer Attributable to it in the District of Gampaha, Sri LankaUnited Nations Population Fund 2012, Accessed January 1 2023 at:https://www.epid.gov.lk/web/images/pdf/HPV/hpv_reaserch_study_findings.pdf

National Cancer Control Programme, Ministry of Health, Sri Lanka National Strategic Plan to Reach the Interim Targets of Cervical Cancer Elimination in Sri Lanka 2021–2030, Accessed 1st January 2023 at:https://www.nccp.health.gov.lk/storage/post/pdfs/National%20Stategic%20plan%20book%202020-11-16.pdf

Balawardena J, Skandarajah T, Rathnayake W, Joseph N. Breast cancer survival in Sri Lanka. JCO Glob Oncol. 2020;6:589–599. [PMC free article] [PubMed] [Google Scholar]

Hewage S A, Samaraweera S, Joseph N, Kularatna S, Gunawardena N. Presentation, diagnosis and treatment delays in breast cancer care and their associations in Sri Lanka, a low-resourced country. Clin Oncol (R Coll Radiol) 2022;34(09):598–607. [PubMed] [Google Scholar]

Rupasinghe T, Silva D C, Balawardena J. Curative intent radiotherapy for squamous cell carcinoma of the head and neck in Sri Lanka: the impact of radiotherapy technique on survival. Clin Oncol (R Coll Radiol) 2021;33(12):765–772. [PubMed] [Google Scholar]

Joseph N, Jayalth H, Balwardena J. Radical external beam radiotherapy in combination with brachytherapy for cervical cancer in Sri Lanka: is treatment delayed treatment denied? JCO Glob Oncol. 2020;6:1574–1581. [PMC free article] [PubMed] [Google Scholar]

Chemoradiotherapy for Cervical Cancer Meta-analysis Collaboration (CCCMAC).

(2010). Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer:

Cochrane Database of Systematic Reviews. https://doi.org/Issue 1. Art. No.: CD008285. DOI:

1002/14651858.CD008285

Reducing uncertainties about the effect of chemoradiotherapy for cervical cancer: individual

data meta-analysis (Review). Cochrane Database of Systematic Reviews 2010; 1:CD008285

Lukka H, Hirte H, Fyles A, Thomas G, Elit L, Johnston M, et al. Concurrent cisplatinbased chemotherapy plus radiotherapy for cervical cancer-a meta-analysis: ClinOncol.

;14(3):203-12.

Peter J. Hoskin. (2006). Radiotherapy in Practice: External Beam Therapy (P. J. Hoskin (ed.); 3rd

Edition). Oxford University Press, 2006. https://books.google.com/books/about/Radiotherapy.

RTOG. 2015. "RTOG 1203 Trial Protocol: A randomized phase III study of standard vs. IMRT

pelvic radiation for postoperative treatment of endometrial and cervical cancer (TIME-C)."

RTOG. 2011. "RTOG 0418 Trial Protocol: Phase II Study of Intensity Modulated Radiation

Therapy (IMRT) to the pelvis +/- chemotherapy for post-operative patients with either

endometrial or cervical carcinoma."

E Alistair J. Hunter, Andre S. Hendriks. Estimation of the effects of radiotherapy treatment

delays on tumor responses: A Review:2020 — The South African Journal of Oncology

Lucas Vitzthum, Jianling Yuan, Daniel Jones, Anne Boldt, Kathryn Dusenbery: Reducing

prolonged chemoradiation treatment times for cervical cancer: BMJ Open Qual. 2019; 8(3):

e000516.

Tergas AI, Neugut AI, Chen L, Burke WM, Hershman DL, Wright JD. Radiation Duration

in Women with Cervical Cancer Treated with Primary Chemoradiation: A Population-Based

Analysis. Cancer Invest. 2016. doi:10.3109/07357907.2015.1131291

Peters WA 3rd, Liu PY, Barrett RJ 2nd, et al. Concurrent chemotherapy and pelvic radiation

therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery

in high-risk early-stage cancer of the cervix: J ClinOncol. 2000;18:1606–13.

Nag S, Erickson B, Thomadsen B, Orton C, Demanes JD, Petereit D. The American

Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of

the cervix. Int J Radiat Oncol Biol Phys. 2000. doi:10.1016/S0360-3016(00)00497-1

KK Lee, JY Lee, JM Nam, CB Kim, KR Park. High-dose-rate vs. low-dose-rate intracavitary

brachytherapy for carcinoma of the uterine cervix: Systematic review and meta-analysisBrachytherapy, 2015 –Elsevier

International Commission on Radiation Units and Measurements. (2016). Brachytherapy

Techniques and Systems. Journal of the International Commission on Radiation Units and

Measurements, Volume 13,(Issue 1-2). https://doi.org/10.1093/jicru/ndw008

5.YJ Kim, HC Kang, YS Kim. Impact of intracavitary brachytherapy technique (2D versus 3D)

on outcomes of cervical cancer: a systematic review and meta-analysis: Strahlentherapie und

Onkologie, 2020 – Springe

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Published

2024-03-11

How to Cite

Mannapperuma, P., Salibi, D., & Tzenios, N. (2024). An Observational Study On Cervical Cancer In Sri Lanka And Its Prevention And Management. Special Journal of the Medical Academy and Other Life Sciences., 2(2). https://doi.org/10.58676/sjmas.v2i2.51

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