Better Strategies For Coronavirus (COVID-19) Vaccination


  • Nikolaos Tzenios c
  • Mohamad Chahine Kursk State Medical University
  • Dr Mary Tazanios Charisma University



hypertension, Cancer


The first case of COVID-19 a coronavirus disease, was reported in December 2019 in Wuhan, China, and spread globally. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is regarded as the most challenging pandemic in the current century. COVID-19 has brought scientists together on a platform where they search for different therapeutic and preventive strategies to combat this coronavirus. Scientists and healthcare workers are working on developing new vaccines that are safe and take less time to develop. They are trying to elucidate various target sites on 2019-nCov that could act as potential candidates for adequate vaccine preparation. Besides this, there is also a need for proper community involvement to elicit the coronavirus disease by taking preventive measures and spreading awareness. In this review, we have focused on how scientists can develop vaccines against new variants and convince the public about vaccine acceptance at the community level. This manuscript reviews Strategies for Covid-19 Vaccination Development, Strategies for Covid-19 Vaccination Acceptance, and Community Engagement in Covid-19 Vaccination plans.


Wang, C., et al., A novel coronavirus outbreak of global health concern. The lancet, 2020. 395(10223): p. 470-473.

Ghebreyesus, T., World Health Organization. WHO Director-General’s opening remarks at the media briefing on COVID-19-25 May 2020. 2020.

Gasmi, A., et al., A global survey in the developmental landscape of possible vaccination strategies for COVID-19. Clinical Immunology, 2022: p. 108958.

Zucman, D., et al. The COVID-19 Pandemic and the Migrant Population for HIV Diagnosis and Care Follow-Up: They Are Left Behind. in Healthcare. 2022. MDPI.

Zhou, F., et al., Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The lancet, 2020. 395(10229): p. 1054-1062.

Dinleyici, E.C., et al., Vaccines and routine immunization strategies during the COVID-19 pandemic. Human vaccines & immunotherapeutics, 2021. 17(2): p. 400-407.

Choi, Y., et al., Vaccination prioritization strategies for COVID-19 in Korea: a mathematical modeling approach. International Journal of Environmental Research and Public Health, 2021. 18(8): p. 4240.

Zhou, W. and W. Wang, Fast-spreading SARS-CoV-2 variants: challenges to and new design strategies of COVID-19 vaccines. Signal transduction and targeted therapy, 2021. 6(1): p. 226.

Strully, K., T. Harrison, and T. Pardo, J Carleo-Evangelist. Strategies to Address Vaccine Hesitancy and Mitigate Health Disparities in Minority Populations. Front Public Health, 23 April 2021. 2021.

Cot, C., et al., Impact of US vaccination strategy on COVID-19 wave dynamics. Scientific Reports, 2021. 11(1): p. 10960.

Benihoud, K., P. Yeh, and M. Perricaudet, Adenovirus vectors for gene delivery. Current opinion in biotechnology, 1999. 10(5): p. 440-447.

Rea, D., et al., Adenoviruses activate human dendritic cells without polarization toward a T-helper type 1-inducing subset. Journal of virology, 1999. 73(12): p. 10245-10253.

Mercado, N., et al., .(2020) Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques. Nature. 586: p. 583-588.

Izda, V., M.A. Jeffries, and A.H. Sawalha, COVID-19: A review of therapeutic strategies and vaccine candidates. Clinical Immunology, 2021. 222: p. 108634.

Schlake, T., et al., Developing mRNA-vaccine technologies. RNA biology, 2012. 9(11): p. 1319-1330.

Karikó, K., et al., Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA. Nucleic acids research, 2011. 39(21): p. e142-e142.

Ye, G., B. Liu, and F. Li, Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain. Nature communications, 2022. 13(1): p. 1214.

Ipekoglu, E., et al., Development and Preclinical Evaluation of Virus Like Particle Vaccine Against COVID-19 Infection. Authorea Preprints, 2021.

Xia, S., K. Duan, and Y. Zhang, Adverse reactions and antibody responses to an inactivated SARS-COV-2 vaccine-interim trial analyses. JAMA, 2020. 324: p. 951-960.

Zhang, Y., et al., Immunogenicity and safety of a SARS-CoV-2 inactivated vaccine in healthy adults aged 18-59 years: report of the randomized, double-blind, and placebo-controlled phase 2 clinical trial. medrxiv, 2020: p. 2020.07. 31.20161216.

Hasan, T., et al., The implementation of mass-vaccination against SARS-CoV-2: a systematic review of existing strategies and guidelines. Vaccines, 2021. 9(4): p. 326.

Dzinamarira, T., et al., COVID-19 vaccine roll-out in South Africa and Zimbabwe: urgent need to address community preparedness, fears and hesitancy. Vaccines, 2021. 9(3): p. 250.

Batool, S., Morton Cuthrell, K., Tzenios, N., & Shehryar, Z. (2022). Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: Emerging Burden. International Research Journal of Oncology, 6(4), 93-104.

Tzenios, N. . (2019). The Impact of Health Literacy on Employee Productivity: An Empirical Investigation . Empirical Quests for Management Essences, 3(1), 21–33. Retrieved from

Tzenios, N. (2019). The Determinants of Access to Healthcare: A Review of Individual, Structural, and Systemic Factors. Journal of Humanities and Applied Science Research, 2(1), 1–14. Retrieved from

Tzenios, N. . (2020). Examining the Impact of EdTech Integration on Academic Performance Using Random Forest Regression. ResearchBerg Review of Science and Technology, 3(1), 94–106. Retrieved from

Tzenios, N. (2023). A New Hallmark of Cancer: Stemness. Special Journal of the Medical Academy and Other Life Sciences., 1(1).

Sharma, P. R., & Tzenios, N. (2023). Impact of Cirrhosis and Alcohol on Mortality Rates and Mitigation Efforts. Special Journal of the Medical Academy and Other Life Sciences., 1(1).

Professor Nikolaos Tzenios Ph.D., FRSPH, FRSM, FAAMFM, FWAMS, FMRS, AcIASS, mRSB, DABAAHP. (2022). CONTRIBUTE TO RAISING AWARENESS IN A COMMUNITY. EPRA International Journal of Multidisciplinary Research (IJMR), 8(12), 122–124. Retrieved from

Tzenios, N. (2020). Clustering Students for Personalized Health Education Based on Learning Styles. Sage Science Review of Educational Technology, 3(1), 22–36. Retrieved from

Tzenios, N. (2022). Student-led Learning Theory. Cambridge Open Engage.

Tzenios, N. (2022). Academic Doctoral Learning Plan. Cambridge Open Engage.

Tzenios N, Tazanios M, Chahine M. The Relationship between Association between Blood Pressure and Risk of Cancer Development.; 2022.

Tzenios, N., Tazanios, M. E., & Chahine, M. (2022). Combining Influenza and COVID-19 Booster Vaccination Strategy to Improve Vaccination Uptake Necessary for Managing the Health Pandemic: A Systematic Review and Meta-Analysis. Vaccines, 11(1), 16.

Tzenios, N. (2022). Interprofessional Program Design Project to improve Nursing students’ attitudes toward collaborative practice. Cambridge Open Engage.

Tzenios, N.; Tazanios, M.; Chahine, M. The impact of BMI on Ovarian Cancer- An Updated Systematic Review and Metanalysis. Preprints 2022, 2022110251 (




How to Cite

Tzenios, N., Chahine, M., & Tazanios, M. (2023). Better Strategies For Coronavirus (COVID-19) Vaccination. Special Journal of the Medical Academy and Other Life Sciences., 1(2).

Most read articles by the same author(s)

1 2 3 > >>