Effects of Smoking on the Human Organism

Authors

DOI:

https://doi.org/10.58676/sjmas.v2i5.72

Keywords:

Passive smoking impacts, Smoking-related diseases, Tobacco use effects, Smoking cessation benefits, Public health policies

Abstract

Background: Smoking is widely recognized for its adverse impacts on health, contributing to chronic and acute conditions affecting nearly every organ system. This review synthesizes the extensive body of research highlighting the physiological and pathological effects of tobacco use.

Methods and Materials: A comprehensive review was conducted using PubMed and additional databases, selecting studies published in the last 25 years. Studies were evaluated for relevance and reliability, focusing on those that provided clear outcomes and substantive evidence on the effects of smoking.

Results: The analysis confirms that smoking is responsible for a significant burden of disease, including major risks for cancers, cardiovascular diseases, respiratory conditions, and reproductive health issues. Smoking increases the risk of lung cancer by 80-90% and is a primary factor in cardiovascular and respiratory diseases. Passive smoking further extends the risk to non-smokers, significantly impacting public health.

Conclusion: Smoking cessation presents substantial benefits, potentially reversing many adverse effects. Public health policies should continue to focus on reducing smoking rates through education, cessation programs, and legislative measures to mitigate the extensive harm caused by tobacco consumption.

References

USUS Department of Health and Human Services. The Health Consequences of Smoking—50 Years of Progress: A Report of the Surgeon General. Atlanta: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2014 [accessed 2016 December 20].

National Center for Chronic Disease Prevention and Health Promotion (USUS.) Office on Smoking and Health. The Health Consequences of Smoking—50 Years of Progress: A Report of the Surgeon General. Atlanta (GAGA): Centers for Disease Control and Prevention (USUS); 2014. http://www.ncbi.nlm.nih.gov/books/NBK179276/.

National Cancer Institute. SEER Stat Fact Sheets: Cancer of Any Site. http://seer.cancer.gov/statfacts/html/all.html.

Müezzinler A, Mons U, Gellert C, et al. Smoking and All-cause Mortality in Older Adults: Results From the CHANCES Consortium. Am J Prev Med. 2015;49(5):e53-e63. doi:10.1016/j.amepre.2015.04.004.

Goldman DP, Zheng Y, Girosi F, et al. The benefits of risk factor prevention in Americans aged 51 years and older. Am J Public Health. 2009;99(11):2096-2101.doi:10.2105/AJPH.2009.172627.

National Cancer Policy Forum, Board on Health Care Services, Institute of Medicine. Reducing Tobacco-Related Cancer Incidence and Mortality: Workshop Summary. Washington (DCDC): National Academies Press (USUS); 2013. http://www.ncbi.nlm.nih.gov/books/NBK206891/.

Centers for Disease Control and Prevention. What Are the Risk Factors for Lung Cancer? https://www.cdc.gov/cancer/lung/basic_info/risk_factors.htm. Published May 31, 2017. Accessed December 1, 2017.

Schwartz AG, Cote ML. Epidemiology of Lung Cancer. Adv Exp Med Biol. 2016;893:21-41. doi:10.1007/978-3-319-24223-1_2

Zuo L, He F, Sergakis GG, et al. Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatments. Am J Physiol Lung Cell Mol Physiol. 2014;307(3):L205-L218. doi:10.1152/ajplung.00330.2013.

Winstanley M, et al., 2015, ‘Chapter 3. The health effects of active smoking’, Tobacco in Australia: Facts and Issues, Cancer Council Victoria.

Win Stanley M, Ford C, Campbell M, 2017, ‘Chapter 4. The health effects of second-hand smoke’, Tobacco in Australia: Facts and Issues, Cancer Council Victoria.

Smoking and respiratory diseases [Article in Japanese] Ishii Y. https://pubmed.ncbi.nlm.nih.gov/23631228/ Nihon Rinsho. 2013;71:416–420.

Diffuse lung diseases in cigarette smokers. Vassallo R. Semin Respir Crit Care Med. 2012;33:533–542.

Smoking-related interstitial pneumonia and pulmonary Langerhans cell histiocytosis. Caminati A, Harari S. Proc Am Thorac Soc. 2006;3:299–306. [

Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) Goeckenjan G. Pneumologie. 2003;57:278–287.

Effects of tobacco smoking on cardiovascular disease. Kondo T, Nakano Y, Adachi S, Murohara T. Circ J. 2019;83:1980–1985.

Cardiovascular toxicity of nicotine: implications for electronic cigarette use. Benowitz NL, Burbank AD. Trends Cardiovasc Med. 2016;26:515–523.

The effects of hookah/waterpipe smoking on general health and the cardiovascular system. Qasim H, Alarabi AB, Alzoubi KH, Karim ZA, Alshbool FZ, Khasawneh FT. Environ Health Prev Med. 2019;24:58.

Cardiovascular effects of Hookah smoking: potential implications for cardiovascular risk. Rezk-Hanna M, Benowitz NL. Nicotine Tob Res. 2019;21:1151–1161.

Waterpipe use and its cardiovascular effects: a systematic review and meta-analysis of case-control, cross-sectional, and non-randomized studies. Mahfooz K, Vasavada AM, Joshi A, et al. Cureus. 2023;15:0.

Effects of cigarette smoking on erectile dysfunction. Kovac JR, Labbate C, Ramasamy R, Tang D, Lipshultz LI. Andrologia. 2015;47:1087–1092.

Smoking and erectile dysfunction: evidence-based analysis. McVary KT, Carrier S, Wessells H. https://pubmed.ncbi.nlm.nih.gov/11586190/ J Urol. 2001;166:1624–1632.

Smoking increases oral mucosa susceptibility to Candida albicans infection via the Nrf2 pathway: In vitro and animal studies. Ye P, Chen W, Huang F, et al. J Cell Mol Med. 2021;25:7948–7960.

The impact of smoking on oral and nasopharyngeal bacterial flora. Brook I. J Dent Res. 2011;90:704–710.

Effects of exposure to smoking on the microbial flora of children and their parents. Brook I. Int J Pediatr Otorhinolaryngol. 2010;74:447–450.

Published

2024-07-01

How to Cite

Gupta, R., Salibi, G., & Tzenios, N. (2024). Effects of Smoking on the Human Organism. Special Journal of the Medical Academy and Other Life Sciences., 2(5). https://doi.org/10.58676/sjmas.v2i5.72

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