Modern methods for the instrumental detection of cognitive impairment in Alzheimer's and dementia patients

Authors

  • Aminath Samha Charisma University, Kursk State Medical University
  • Dr.Ghassan Salibi Charisma University, Kursk State Medical University

DOI:

https://doi.org/10.58676/sjmas.v1i1.9

Keywords:

Dementia, Alzheimer's disease, cognitive impairment

Abstract

Patients with cognitive impairment diseases are no longer fully oriented to time and space. The disease may be the root cause of all cognitive impairments (CI). Depending on the precise diagnosis, different cognitive disorders require different treatments. The three major goals of neuroimaging in Alzheimer's disease (AD) are to detect very early AD at a prodromal stage of moderate cognitive impairment, to differentiate AD from other dementia-causing illnesses, and to forecast the progression of MCI to AD. Consequently, this study's objective is to examine the most sensitive instrumental testing techniques for the early identification of cognitive deterioration in AD and dementia patients.

References

WHO, ageing and health, key facts

https://www.who.int/news-room/fact-sheets/detail/ageing-and-health#:~:text=The%20pace%20of%20population%20ageing,from%2012%25%20to%2022%25.

WHO, Dementia

https://www.who.int/news-room/fact-sheets/detail/dementia

Heiss, WD., Rosenberg, G.A., Thiel, A. et al. Neuroimaging in vascular cognitive impairment: a state-of-the-art review. BMC Med 14, 174 (2016). https://doi.org/10.1186/s12916-016-0725-0

Dementia Australia, Types of Dementia

https://www.dementia.org.au/information/about-dementia/types-of-dementia

J. Hort, J. T. O’Brien, G. Gainotti, T. Pirttila, B. O. Popescu, I. Rektorova, S. Sorbi, P. Scheltens, on behalf of the EFNS Scientist Panel on Dementia, EFNS guidelines for the diagnosis and management of Alzheimers disease,2010 Sep; 17(10); 1236-1248

https://doi.org/10.1111/j.1468-1331.2010.03040.x

Lane CA, Hardy J, Schott JM. Alzheimer's disease. Eur J Neurol. 2018 Jan;25(1):59-70. doi: 10.1111/ene.13439. Epub 2017 Oct 19. PMID: 28872215. https://onlinelibrary.wiley.com/doi/10.1111/ene.13439

Breijyeh Z, Karaman R. Comprehensive Review on Alzheimer's Disease: Causes and Treatment. Molecules. 2020 Dec 8;25(24):5789. doi: 10.3390/molecules25245789. PMID: 33302541; PMCID: PMC7764106.

https://www.mdpi.com/1420-3049/25/24/5789#B8-molecules-25-05789

Tartaglia MC, Rosen HJ, Miller BL. Neuroimaging in Dementia. Neurotherapeutics. 2011 Jan;8(1):82-92. doi: 10.1007/s13311-010-0012-2. PMID: 21274688; PMCID: PMC3026935.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026935/

NICE guideline, Dementia: assessment, management and support for people living with Dementia and their care, 20 June 2018

https://www.nice.org.uk/guidance/ng97/resources/dementia-assessment-management-and-support-for-people-living-with-dementia-and-their-carers-pdf-1837760199109

Matsuda H. Role of neuroimaging in Alzheimer's disease, with emphasis on brain perfusion SPECT. J Nucl Med. 2007 Aug;48(8):1289-300. doi: 10.2967/jnumed.106.037218. Epub 2007 Jul 13. PMID: 17631544.

https://pubmed.ncbi.nlm.nih.gov/17631544/

Heiss, WD., Rosenberg, G.A., Thiel, A. et al. Neuroimaging in vascular cognitive impairment: a state-of-the-art review. BMC Med 14, 174 (2016). https://doi.org/10.1186/s12916-016-0725-0

Knopman DS, Parisi JE, Boeve BF, Cha RH, Apaydin H, Salviati A, Edland SD, Rocca WA. Vascular Dementia in a population-based autopsy study. Arch Neurol. 2003 Apr;60(4):569-75. doi: 10.1001/archneur.60.4.569. PMID: 12707071.

https://pubmed.ncbi.nlm.nih.gov/12707071/

Malojcic, B., Giannakopoulos, P., Sorond, F.A. et al. Ultrasound and dynamic functional imaging in vascular cognitive impairment and Alzheimer’s disease. BMC Med 15, 27 (2017).

https://doi.org/10.1186/s12916-017-0799-3

Jellinger KA. The enigma of vascular cognitive disorder and vascular Dementia. Acta Neuropathol. 2007 Apr;113(4):349-88. doi: 10.1007/s00401-006-0185-2. Epub 2007 Feb 7. PMID: 17285295.

https://pubmed.ncbi.nlm.nih.gov/17285295/

Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular Cognitive Impairment and Dementia: JACC Scientific Expert Panel. J Am Coll Cardiol. 2019 Jul 2;73(25):3326-3344. doi: 10.1016/j.jacc.2019.04.034. PMID: 31248555; PMCID: PMC6719789.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719789/

Kasban H., El-Bendary M. A. M., Salama D. H. A comparative study of medical imaging techniques. International Journal of Information Science and Intelligent System . 2015;4(2):37–58.

https://ilearn.thdeg.de/pluginfile.php/480243/mod_book/chapter/8248/updated_JXIJSIS2015.pdf

Hussain S, Mubeen I, Ullah N, Shah SSUD, Khan BA, Zahoor M, Ullah R, Khan FA, Sultan MA. Modern Diagnostic Imaging Technique Applications and Risk Factors in the Medical Field: A Review. Biomed Res Int. 2022 Jun 6;2022:5164970. doi: 10.1155/2022/5164970. PMID: 35707373; PMCID: PMC9192206.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192206/#B2

Zhang J., Chen K. Wang D., Gao F., Zheng Y and Yang M (2020) Editorial: Advances of neuroimaging and Data Analysis Front. Neurol. 11:257, 08th April 2020

https://www.frontiersin.org/articles/10.3389/fneur.2020.00257/full

Knott L., Willacy H. Computer Tomography, CT scans, 19th October 2021

https://patient.info/doctor/computerised-tomography-ct-scans

Fertikh D. MD, Caroline R Taylor, MD, Head Computed Tomography Scanning,29th December 2020

https://emedicine.medscape.com/article/2110836-overview#showall

William Herring, MD, FACR, Daniel J. Kowal, MD, LEARNING RADIOLOGY Recognizing the Basics 4th Edition, chapter 21

file:///C:/Users/amina/Downloads/Learning%20Radiology_%20Recognizing%20the%20Basics%204th%20Edition.pdf

Mr Richard McIntyre, Prof Stacy Goergen, Magnetic Resonance Imaging (MRI), 18/8/2017.

https://www.insideradiology.com.au/mri-hp/

Omar Islam, MD, FRCPC , Sohaib Munir , Mahan Mathur, MD, Brain Magnetic Resonance Imaging periprocedural Care, Medscape,Nov 06, 2019

https://emedicine.medscape.com/article/2105033-periprocedure#b6

Sushmita Purkayastha, PhD, Farzaneh Sorond, MD, PhD, Transcranial Doppler Ultrasound: Technique and Application, September 2012, Seminars in Neurology 32(4):411-20

https://www.researchgate.net/publication/235382817_Transcranial_Doppler_Ultrasound_Technique_and_Application

Bathala L, Mehndiratta MM, Sharma VK. Transcranial doppler: Technique and common findings (Part 1). Ann Indian Acad Neurol. 2013 Apr;16(2):174-9. doi: 10.4103/0972-2327.112460. PMID: 23956559; PMCID: PMC3724069.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724069/

Youngrok Do, Yong-Jae Kim, Jun Hong Lee, Transcranial Doppler: examination techniques and interpretation, Annals of Clinical Neurophysiology 2019; 21(2): 71-78., 30 July 2019

https://doi.org/10.14253/acn.2019.21.2.71

Yuxiao Wan, Xiufei Teng, Shiyi Li and Yanchao Yang , Application of transcranial Doppler in cerebrovascular diseases, Frontiers in Aging Neuroscience, November 2022

https://www.frontiersin.org/articles/10.3389/fnagi.2022.1035086/full

Alexander L. Loomis; Mathew N. Chakko.,Doppler Trans-Cranial Assessment, Protocols, And Interpretation, Treasure Island (FL): StatPearls Publishing; 2022 Jan

https://www.ncbi.nlm.nih.gov/books/NBK570636/

Purkayastha S, Sorond F. Transcranial Doppler ultrasound: technique and application. Semin Neurol. 2012 Sep;32(4):411-20. doi: 10.1055/s-0032-1331812. Epub 2013 Jan 29. PMID: 23361485; PMCID: PMC3902805.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902805/

Bathala L, Mehndiratta MM, Sharma VK. Transcranial doppler: Technique and common findings (Part 1). Ann Indian Acad Neurol. 2013 Apr;16(2):174-9. doi: 10.4103/0972-2327.112460. PMID: 23956559; PMCID: PMC3724069.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724069/

NHS, Tests for diagnosing Dementia, Dementia guide

https://www.nhs.uk/conditions/dementia/diagnosis-tests/?tabname=symptoms-and-diagnosis

Mathew R. Ayers, DO; Diana Svaldi, PhD; and Liana G. Apostolova, MD, MS, Brain Imaging in Differential Diagnosis of Dementia, JUNE 2019,

https://practicalneurology.com/articles/2019-june/brain-imaging-in-differential-diagnosis-of-dementia

Harper L, Barkhof F, Scheltens P, et al. J Neurol Neurosurg Psychiatry 2014;85: 692–698.

https://jnnp.bmj.com/content/jnnp/85/6/692.full.pdf

Frederik Barkhof, Marieke Hazewinkel, Maja Binnewijzend and Robin Smithuis, Alzheimer Centre and Image Analysis Centre, Vrije Universiteit Medical Center, Amsterdam and the Alrijne Hospital, Leiderdorp, The Netherlands, Dementia - Role of MRI

https://radiologyassistant.nl/neuroradiology/dementia/role-of-mri

Shi F, Liu B, Zhou Y, Yu C, Jiang T. Hippocampal volume and asymmetry in mild cognitive impairment and Alzheimer's disease: Meta-analyses of MRI studies. Hippocampus. 2009 Nov;19(11):1055-64. doi: 10.1002/hipo.20573. PMID: 19309039.

https://pubmed.ncbi.nlm.nih.gov/19309039/

Vemuri, P., Jack, C.R. Role of structural MRI in Alzheimer's disease. Alz Res Therapy 2, 23 (2010).

https://doi.org/10.1186/alzrt47

Mary Ellen Koran, MD, PhD, Neuroimaging and Alzheimer’s Disease

https://practicalneurology.com/articles/2019-nov-dec/neuroimaging-and-alzheimers-disease

Malojcic B, Giannakopoulos P, Sorond FA, Azevedo E, Diomedi M, Oblak JP, Carraro N, Boban M, Olah L, Schreiber SJ, Pavlovic A, Garami Z, Bornstein NM, Rosengarten B. Ultrasound and dynamic functional imaging in vascular cognitive impairment and Alzheimer's disease. BMC Med. 2017 Feb 9;15(1):27. doi: 10.1186/s12916-017-0799-3. PMID: 28178960; PMCID: PMC5299782.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299782/

Nicodemus NE, Becerra S, Kuhn TP, Packham HR, Duncan J, Mahdavi K, Iovine J, Kesari S, Pereles S, Whitney M, Mamoun M, Franc D, Bystritsky A, Jordan S. Focused transcranial ultrasound for treatment of neurodegenerative Dementia. Alzheimers Dement (N Y). 2019 Aug 8;5:374-381. doi: 10.1016/j.trci.2019.06.007. PMID: 31440580; PMCID: PMC6700262.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700262/

Anstey KJ, Cherbuin N, Budge M, Young J. Body mass index in midlife and late-life as a risk factor for Dementia: a meta-analysis of prospective studies. Obes Rev. 2011 May;12(5):e426-37. doi: 10.1111/j.1467-789X.2010.00825.x. Epub 2011 Feb 23. PMID: 21348917.

https://onlinelibrary.wiley.com/doi/10.1111/j.1467-789X.2010.00825.x

Sharp SI, Aarsland D, Day S, Sønnesyn H; Alzheimer's Society Vascular Dementia Systematic Review Group, Ballard C. Hypertension is a potential risk factor for vascular Dementia: systematic review. Int J Geriatr Psychiatry. 2011 Jul;26(7):661-9. doi: 10.1002/gps.2572. Epub 2010 Dec 29. PMID: 21495075.

https://onlinelibrary.wiley.com/doi/10.1002/gps.2572

Hannah A.D. Keage, Owen F. Churches, Mark Kohler, Danielle Pomeroy, Rocco Luppino, Michelle L. Bartolo a Scott Elliott, Cerebrovascular Function in Aging and Dementia: A Systematic Review of Transcranial Doppler Studies, DOI: 10.1159/000339234, Published online: June 29, 2012

https://www.karger.com/article/pdf/339234

Lim JS, Lee JY, Kwon HM, Lee YS. The correlation between cerebral arterial pulsatility and cognitive dysfunction in Alzheimer's disease patients. J Neurol Sci. 2017 Feb 15;373:285-288. doi: 10.1016/j.jns.2017.01.001. Epub 2017 Jan 4. PMID: 28131207.

https://pubmed.ncbi.nlm.nih.gov/28131207/

Roher AE, Garami Z, Tyas SL, Maarouf CL, Kokjohn TA, Belohlavek M, Vedders LJ, Connor D, Sabbagh MN, Beach TG, Emmerling MR. Transcranial doppler ultrasound blood flow velocity and pulsatility index as systemic indicators for Alzheimer's disease. Alzheimers Dement. 2011 Jul;7(4):445-55. doi: 10.1016/j.jalz.2010.09.002. Epub 2011 Mar 9. PMID: 21388892; PMCID: PMC3117072.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117072/

Fashanu, H., Tazanios, M., & Tzenios, N. (2022). HEALTH PROMOTION PROGRAM. Cambridge Open Engage. https://doi.org/10.33774/coe-2022-kc0f4

Tzenios, N. (2022, December 25). Higher medical education and covid vaccination. https://doi.org/10.31219/osf.io/x5apd

Tzenios, N. (2019). The Determinants of Access to Healthcare: A Review of Individual, Structural, and Systemic Factors. Journal of Humanities and Applied Science Research, 2(1), 1–14. Retrieved from https://journals.sagescience.org/index.php/JHASR/article/view/23

Tzenios, N. (2022). Interprofessional Program Design Project to improve Nursing students’ attitudes toward collaborative practice. Cambridge Open Engage. https://doi.org/10.33774/coe-2022-hsxz7

Professor Nikolaos Tzenios Ph.D., FRSPH, FRSM, FAAMFM, FWAMS, FMRS, AcIASS, mRSB, DABAAHP. (2022). CONTRIBUTE TO RAISING AWARENESS IN A COMMUNITY. EPRA International Journal of Multidisciplinary Research (IJMR), 8(12), 122–124. Retrieved from http://eprajournals.net/index.php/IJMR/article/view/1252.(https://doi.org/10.36713/epra12021)

Tzenios, N. (2022). Student-led Learning Theory. Cambridge Open Engage. https://doi.org/10.33774/coe-2022-0x2bx

Tzenios, N. (2022). Academic Doctoral Learning Plan. Cambridge Open Engage. https://doi.org/10.33774/coe-2022-7twh9

Downloads

Published

2023-01-20

How to Cite

Samha, A., & Salibi, D. (2023). Modern methods for the instrumental detection of cognitive impairment in Alzheimer’s and dementia patients. Special Journal of the Medical Academy and Other Life Sciences., 1(1). https://doi.org/10.58676/sjmas.v1i1.9

Issue

Section

Articles

Most read articles by the same author(s)

1 2 > >>